Treatment Protocol
Repair
Treatment Protocol
Repair
During the Repair phase, you focus on providing your body with the nutrients it needs to heal your gut lining. This phase is crucial because a damaged gut lining (sometimes referred to as ‘leaky gut’) allows undigested food particles, toxins, and microbes to pass into the bloodstream, causing inflammation and other health issues.
Goal:
- Repair Gut Integrity
Gut Integrity
Goal: fortify and restore the intestinal barrier and mucus lining.
Gut Lining:
- L-Glutamine: essential for the repair and growth of intestinal cells.
- Zinc Carnosine: adheres to the stomach lining, where it helps in tissue repair and inhibiting inflammatory responses. Protects and stabilizes the gastrointestinal mucosa and enhances gut barrier function.
- SCFAs (tributyrin): a postbiotic that supports the production of healthy gut mucus, provides energy to colon cells, and maintains an optimal pH level in the gut.
Intestinal Mucus Barrier:
- N-acetylglucosamine (NAG): combines with mucin secreted from goblet cells, enhancing the mucus barrier’s protective function.
- Choline (CDP Choline): supports the synthesis of acetylcholine, which stimulates goblet cell degranulation, leading to increased secretion of mucus in the intestinal lining.
- Vitamin B5 (Pantothenic acid): supports the synthesis of acetylcholine, which stimulates goblet cell degranulation, leading to increased secretion of mucus in the intestinal lining.
Immunity:
- Colostrum: one of the few interventions that can boost mucosal immunity with immunoglobulins, including IgA.
- Vitamin D: has broad anti-inflammatory and immunomodulatory effects. Strengthens the intestinal barrier, and supports immune response.
Anti-inflammatory:
- Omega-3 Fatty Acids (EPA/DHA): reduce inflammation by modulating inflammatory pathways and cytokine production, also strengthening the gut barrier against inflammatory damage.
- Boswellia: targets specific inflammatory pathways relevant to joint and gut health.
Testing
Goal: evaluate digestive function.
Serum Zonulin
- How It Works: measures the levels of Zonulin in the blood, a protein that modulates gut permeability. Elevated levels may indicate a compromised gut barrier.
- Usage: initial assessment to establish baseline gut permeability and periodic follow-ups to track treatment efficacy.
Fecal Calprotectin
- How It Works: measures the level of calprotectin, a protein marker of inflammation, in the stool. High levels can indicate gut inflammation and issues with gut integrity.
- Usage: at the start of treatment for baseline measurement and subsequently to monitor treatment response.
Patient-Reported Outcome Measures (PROMs)
- How It Works: consists of brief surveys about symptoms, lifestyle, and well-being. These scores help us understand how you’re feeling beyond what tests can show.
- Usage: administered at key stages to correlate with other test results and to gauge subjective improvements in gut health and overall well-being.