Treatment Protocol
Reinoculate
Treatment Protocol
Reinoculate
Reinoculate is a critical stage in gut restoration, focusing on rebuilding the gut flora by fostering an environment conducive to the reintroduction and flourishing of beneficial bacteria.
**Goals:**
- Balance Microbiome
1. Toxin support
Goal: Remove toxins to reduce symptoms of microbial die-off during fasting or gut cleanse.
- Binding Support
- What is it: Binding harmful toxins like lipopolysaccharides (LPS) to clear them from the system.
- How it works: Use immunoglobulins to bind a wide range of toxins and support immune function.
- Detoxification Pathway Support
- What it is: Enhancing the body’s natural detoxification processes.
- How it works: Use milk thistle and sulforaphane to support liver function, aiding in the removal of toxins.
2. Fasting
Goal: Starve harmful bacteria and strengthen the gut, setting the stage for the reintroduction of beneficial strains.
- How it works: 36-hour fasting, you weaken pathogenic bacteria and strengthen the gut’s defense. A good duration for balancing safety, efficacy, and compliance.
- Important considerations: Proper hydration and electrolyte balance are key. Pregnant women and those underweight should not fast. Fasting mimicking diet can be considered as an alternative for certain patients.
3. Feed-to-kill
Goal: Strategically target harmful bacteria.
- How it works: Specific feeding strategies can be used to make certain harmful bacteria more susceptible to antimicrobial agents during the gut cleanse.
4. Gut cleanse
Goal: Remove waste and harmful bacteria to prepare the gut for reinoculation.
- Antimicrobial Support: Natural antimicrobials such as allicin (garlic), oregano oil, berberine, curcumin, or caprylic acid for fungal issues. Biocidin, Candibactin-AR/BR, and FC-Cidal with Dysbiocide are medicine options. Atrantil for methane-targeting.
- Biofilm Disruptors: Using agents like N-acetylcysteine (NAC) and InterFase Plus by Klaire Labs.
- Monitoring: Ensure that there are no interactions with medications and tailoring the approach to individual needs as the gut cleanse can produce side-effects.
5. Targeted Probiotics and Prebiotics
Goal: Introduce and nourish beneficial bacteria.
- How it works: Specific probiotics beneficial to the individual are introduced and targeted nutrients (prebiotics) are provided to nourish them.
- Personalization: Customized selection based on individual gut profile and needs.
6. Fermented foods
Goal: Support gut health through the dietary inclusion of naturally probiotic-rich foods.
- How it works: Including various fermented foods in the diet (kefir, kimchi, sauerkraut, natto, yogurt, etc.) introduces beneficial bacteria and supports overall gut health.
Testing
Goal: Assess and monitor the gut microbiota composition.
Core:
- 16S rRNA Sequencing
- How It Works: Utilizes the 16S rRNA gene to identify and compare bacteria present in the gut microbiome.
- Usage: Initial assessment and periodic follow-ups for microbiome diversity and composition changes.
- Patient-Reported Outcome Measures (PROMs)
- How It Works: Consists of brief surveys about symptoms. These scores help us understand how you’re feeling during reinoculation.
- Usage: Administered at key stages to track symptom changes and correlate with microbial shifts.
Conditional:
- SIBO Breath Test
- How It Works: Measures the concentration of hydrogen and methane gases in your breath, which can indicate Small Intestinal Bacterial Overgrowth (SIBO).
- Usage: Administered as a follow-up post-treatment to confirm eradication.